Sunday, December 14, 2008

The dread -lcrt0.o error on Mac OS X

I periodically run into this problem compiling software on the mac:

ld_classic: can't locate file for: -lcrt0.o
collect2: ld returned 1 exit status
make: *** [muscle] Error 1

In this case, I was compiling MUSCLE, a multiple alignment program.

The solution is to track the -static flag down in your Makefile, and remove it. GCC/OSX does NOT like -static.


Anonymous said...

I just fixed this in another bioinformatics app. (nhPhyml) by removing the -static flag.

Kris Kowal said...


Anonymous said...

Many thanks.

Anonymous said...

Fixed my problems with Augustus (gene predictor) too. Thanks

Anonymous said...


Izra said...

Excellent, thanks for the trick